Article
Asymmetry in kinesin walking.
Biochemistry - 7 Aug 2007
Shao Qiang, Gao Yi Qin
Abstract excerpt
Several lines of experimental evidence suggest that the conventional kinesin 1 walks by an asymmetric hand-over-hand mechanism, although it is a homodimer. In the previous study, we examined several important force-dependent features of the hand-over-hand mechanism of kinesin. In this study, we focus on the asymmetry in the hand-over-hand mechanism. We show that the experimentally observed kinesin limping can be...
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