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Article

Assessing methods for identifying pair-wise atomic contacts across binding interfaces.

Journal of structural biology - 1 Feb 2006

Fischer Tiffany B, Holmes J Bradley, Miller Ian R, Parsons Jerod R, Tung Leon, Hu James C, Tsai Jerry

Abstract excerpt

An essential step in understanding the molecular basis of protein-protein interactions is the accurate identification of inter-protein contacts. We evaluate a number of common methods used in analyzing protein-protein interfaces: a Voronoi polyhedra-based approach, changes in solvent accessible surface area (DeltaSASA) and various radial cutoffs (closest atom, Cbeta, and centroid). First, we compared the Voronoi...

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Identifiers

PMID: 16377205
DOI: 10.1016/j.jsb.2005.11.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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