Article
Genotypic resistance to lamivudine among hepatitis B virus isolates in Mexico.
The Journal of antimicrobial chemotherapy - 1 Feb 2006
Alvarado-Esquivel Cosme, de la Ascensión Carrera-Gracia Manuela, Conde-González Carlos Jesús, Juárez-Figueroa Luis, Ruiz-Maya Lilia, Aguilar-Benavides Sergio, Torres-Valenzuela Alejandro, Sablon Erwin
Abstract excerpt
BACKGROUND: Drug resistance of hepatitis B virus (HBV) is an increasing clinical problem. Resistance to lamivudine in HBV isolates in Mexico has been poorly explored. OBJECTIVES: To characterize the mutation patterns associated with genotypic resistance to lamivudine and their prevalence among HBV isolates in Mexico. MATERIAL AND METHODS: Thirty-nine Mexican HBV isolates were analysed by PCR and line probe assay...
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