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Article

Targeting phenotypic heterogeneity in benign prostatic hyperplasia.

Differentiation; research in biological diversity - 1 Jan 2000

Strand Douglas W, Costa Daniel N, Francis Franto, Ricke William A, Roehrborn Claus G

Abstract excerpt

Benign prostatic hyperplasia and associated lower urinary tract symptoms remain difficult to treat medically, resulting in hundreds of thousands of surgeries performed annually in elderly males. New therapies have not improved clinical outcomes since alpha blockers and 5 alpha reductase inhibitors were introduced in the 1990s. An underappreciated confounder to identifying novel targets is pathological...

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Identifiers

PMID: 28800482
DOI: 10.1016/j.diff.2017.07.005
PMCID: PMC5669834

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