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Article

Production of reactive oxygen species in response to replication stress and inappropriate mitosis in fission yeast.

Journal of cell science - 1 Jan 2006

Marchetti Maria A, Weinberger Martin, Murakami Yota, Burhans William C, Huberman Joel A

Abstract excerpt

Previous studies have indicated that replication stress can trigger apoptosis-like cell death, accompanied (where tested) by production of reactive oxygen species (ROS), in mammalian cells and budding yeast (Saccharomyces cerevisiae). In mammalian cells, inappropriate entry into mitosis also leads to cell death. Here, we report similar responses in fission yeast (Schizosaccharomyces pombe). We used ROS- and...

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Identifiers

PMID: 16371652
DOI: 10.1242/jcs.02703
PMCID: PMC1582148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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