Article
Tests of linkage and association of PTH/PTHrP receptor type 1 gene with bone mineral density and height in Caucasians.
Journal of bone and mineral metabolism - 1 Jan 2006
Zhang Yuan-Yuan, Liu Peng-Yuan, Lu Yan, Xiao Peng, Liu Yong-Jun, Long Ji-Rong, Shen Hui, Zhao Lan-Juan, Elze Leo, Recker Robert R, Deng Hong-Wen
Abstract excerpt
Parathyroid hormone/parathyroid hormone-related peptide receptor type 1 (PTHR1) plays an important role in calcium metabolism. It was previously shown to influence variation in bone mineral density (BMD). To investigate its importance in a typical U.S. Caucasian population, we tested linkage or association of the PTHR1 gene with BMD and height. Altogether, 1873 subjects from 405 Caucasian nuclear families were...
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