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Article

Dihydrolipoamide acyltransferase is critical for Mycobacterium tuberculosis pathogenesis.

Infection and immunity - 1 Jan 2006

Shi Shuangping, Ehrt Sabine

Abstract excerpt

Mycobacterium tuberculosis has evolved to persist in host macrophages, where it faces a nutrient-poor environment and is exposed to oxidative and nitrosative stress. To defend itself against oxidative/nitrosative stress, M. tuberculosis expresses an NADH-dependent peroxidase and peroxynitrite reductase that is encoded by ahpC, ahpD, lpd, and dlaT. In addition to its central role in the peroxynitrite reductase...

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Identifiers

PMID: 16368957
DOI: 10.1128/IAI.74.1.56-63.2006
PMCID: PMC1346611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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