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Article

Endothelial activation and induction of monocyte adhesion by nontransferrin-bound iron present in human sera.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 Feb 2006

Kartikasari Apriliana E R, Georgiou Niki A, Visseren Frank L J, van Kats-Renaud Henny, van Asbeck B Sweder, Marx Joannes J M

Abstract excerpt

Nontransferrin-bound iron (NTBI) has been detected in iron overload diseases. This form of iron may exert pro-oxidant effects and modulate cellular function and inflammatory response. The present study has aimed to investigate the effects of serum NTBI on monocyte adherence to endothelium. Measured by a recently developed high-throughput fluorescence-based assay, serum NTBI was found to be higher in both...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16368718
DOI: 10.1096/fj.05-4700fje

Genes

HFE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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