Article
Non-transferrin-bound iron is associated with plasma level of soluble intercellular adhesion molecule-1 but not with in vivo low-density lipoprotein oxidation.
Atherosclerosis - 1 Sept 2007
van Tits L J H, Jacobs E M G, Swinkels D W, Lemmers H L M, van der Vleuten G M, de Graaf J, Stalenhoef A F H
Abstract excerpt
BACKGROUND: Excess body iron is associated with increased cardiovascular disease risk, possibly via non-transferrin-bound iron (NTBI)-mediated enhancement of inflammation and oxidation of low-density lipoprotein (LDL). METHODS: We assessed this proposed atherosclerotic mechanism of body iron by determining the relationship of levels of serum iron parameters, including NTBI, with plasma markers of inflammation and...
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