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Article

Crystal structure of a clip-domain serine protease and functional roles of the clip domains.

The EMBO journal - 21 Dec 2005

Piao Shunfu, Song Young-Lan, Kim Jung Hyun, Park Sam Yong, Park Ji Won, Lee Bok Leul, Oh Byung-Ha, Ha Nam-Chul

Abstract excerpt

Clip-domain serine proteases (SPs) are the essential components of extracellular signaling cascades in various biological processes, especially in embryonic development and the innate immune responses of invertebrates. They consist of a chymotrypsin-like SP domain and one or two clip domains at the N-terminus. Prophenoloxidase-activating factor (PPAF)-II, which belongs to the noncatalytic clip-domain SP family,...

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Identifiers

PMID: 16362048
DOI: 10.1038/sj.emboj.7600891
PMCID: PMC1356332

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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