Article
Proceedings of the SMBE Tri-National Young Investigators' Workshop 2005. Molecular genetics of natural populations.
Molecular biology and evolution - 1 May 2006
Greenberg Anthony J, Wu Chung-I
Abstract excerpt
Significant progress in evolutionary genetics has been made by studying, on the one hand, patterns of DNA sequence polymorphism and, on the other, genetic architecture of complex adaptive traits. However, connections between nucleotide variants under selection and adaptively relevant phenotypes are missing. Such connections can be established using precise gene replacement. We review the recent successful...
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