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Article

Differentiated rabbit prostatic stromal cells in primary culture display functional alpha1A-adrenoceptors.

Neurourology and urodynamics - 1 Jan 2006

Boulbès Delphine, Choquet Armelle, Barrère-Lemaire Stéphanie, Costa Pierre, Soustelle Laurent, Nargeot Joël, Bali Jean-Pierre, Hollande Frédéric, Magous Richard

Abstract excerpt

AIMS: BPH is characterized by uncontrolled proliferation and increased contractility of prostatic smooth muscle cells. The activation of alpha1-adrenoceptors (alpha1-AR) seems involved in the latter event, but the lack of in vitro models expressing these receptors has hampered a more specific characterization of their role. In order to do so, we attempted to develop a new model of rabbit cultured prostatic...

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PMID: 16355401
DOI: 10.1002/nau.20196

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