Article
Genetics of type 1 diabetes: similarities and differences between Asian and Caucasian populations.
Annals of the New York Academy of Sciences - 1 Oct 2006
Ikegami Hiroshi, Fujisawa Tomomi, Kawabata Yumiko, Noso Shinsuke, Ogihara Toshio
Abstract excerpt
Transracial studies are a powerful tool for genetic association studies of multifactorial diseases, such as type 1 diabetes. We therefore studied the association of candidate genes, HLA, INS, CTLA4, PTPN22, and SUMO4, with type 1 diabetes in Asian populations in comparison with Caucasian populations. Class II HLA was strongly associated with type 1 diabetes in both Asian and Caucasian populations, but alleles...
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