Article
[Effect of the XRCC1 and XRCC3 genetic polymorphisms on the efficacy of platinum-based chemotherapy in patients with advanced non-small cell lung cancer].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 1 Dec 2011
Xu Chong'an, Wang Xiaojie, Zhang Ye, Li Lin
Abstract excerpt
BACKGROUND AND OBJECTIVE: DNA repair gene polymorphisms can be used to predict the sensitivity of platinum-based chemotherapy. Thus, such polymorphisms are important for the individual treatment of non-small cell lung cancer (NSCLC). The aim of this study is to investigate the relationship between X-ray repair cross complementing protein 1 (XRCC1) and X-ray repair cross complementing protein 3 (XRCC3) gene...
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