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Article

Differentiated functions of Ras1 and Ras2 proteins in regulating the germination, growth, conidiation, multi-stress tolerance and virulence of Beauveria bassiana.

Environmental microbiology - 1 Feb 2013

Xie Xue-Qin, Guan Yi, Ying Sheng-Hua, Feng Ming-Guang

Abstract excerpt

Ras1 and Ras2 are two distinct Ras GTPases in Beauveria bassiana, an entomopathogenic fungus whose biocontrol potential against insect pests depends largely on virulence and multi-stress tolerance. The functions of both proteins were characterized for the first time by constructing dominant-active (GTP-bound) Ras1(G19V) and dominant-negative (GDP-bound) Ras1(D126A) and integrating them and normal Ras1 into wild...

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PMID: 22958161
DOI: 10.1111/j.1462-2920.2012.02871.x

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