Article
Matrix metalloproteinase 2 is associated with stable and matrix metalloproteinases 8 and 9 with vulnerable carotid atherosclerotic lesions: a study in human endarterectomy specimen pointing to a role for different extracellular matrix metalloproteinase inducer glycosylation forms.
Stroke - 1 Jan 2006
Sluijter Joost P G, Pulskens Wilco P C, Schoneveld Arjan H, Velema Evelyn, Strijder Chaylendra F, Moll Frans, de Vries Jean-Paul, Verheijen Jan, Hanemaaijer Roeland, de Kleijn Dominique P V, Pasterkamp Gerard
Abstract excerpt
BACKGROUND AND PURPOSE: We studied matrix metalloproteinases (MMP) 2, 8, and 9 and extracellular matrix metalloproteinase inducer (EMMPRIN) levels in relation to carotid atherosclerotic plaque characteristics. METHODS: Carotid atherosclerotic plaques (n=150) were stained and analyzed for the presence of collagen, smooth muscle cell (SMC), and macrophages. Adjacent segments were used to isolate total protein to...
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