Article
Selective sweep mapping of genes with large phenotypic effects.
Genome research - 1 Dec 2005
Pollinger John P, Bustamante Carlos D, Fledel-Alon Adi, Schmutz Sheila, Gray Melissa M, Wayne Robert K
Abstract excerpt
Many domestic dog breeds have originated through fixation of discrete mutations by intense artificial selection. As a result of this process, markers in the proximity of genes influencing breed-defining traits will have reduced variation (a selective sweep) and will show divergence in allele frequency. Consequently, low-resolution genomic scans can potentially be used to identify regions containing genes that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
