Article
An heuristic filtering tool to identify phenotype-associated genetic variants applied to human intellectual disability and canine coat colors.
BMC bioinformatics - 19 Nov 2015
Broeckx Bart J G, Coopman Frank, Verhoeven Geert, Bosmans Tim, Gielen Ingrid, Dingemanse Walter, Saunders Jimmy H, Deforce Dieter, Van Nieuwerburgh Filip
Abstract excerpt
BACKGROUND: Identification of one or several disease causing variant(s) from the large collection of variants present in an individual is often achieved by the sequential use of heuristic filters. The recent development of whole exome sequencing enrichment designs for several non-model species created the need for a species-independent, fast and versatile analysis tool, capable of tackling a wide variety of...
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