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Article

Gamma interferon is dispensable for neopterin production in vivo.

Clinical and diagnostic laboratory immunology - 1 Dec 2005

Sghiri R, Feinberg J, Thabet F, Dellagi K, Boukadida J, Ben Abdelaziz A, Casanova J L, Barbouche M R

Abstract excerpt

Previous studies have indicated that neopterin is synthesized in vitro by human monocyte-derived macrophages and dendritic cells upon stimulation with gamma interferon (IFN-gamma). Neopterin production under specific conditions in vitro has also been obtained upon stimulation with IFN-alpha and/or IFN-beta. However, it is unknown if any IFN-gamma-independent neopterin synthesis is possible in vivo. In the present...

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Identifiers

PMID: 16339068
DOI: 10.1128/CDLI.12.12.1437-1441.2005
PMCID: PMC1317069

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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