Article
Overexpression of apolipoprotein A-IV enhances lipid secretion in IPEC-1 cells by increasing chylomicron size.
The Journal of biological chemistry - 10 Feb 2006
Lu Song, Yao Ying, Cheng Xiangying, Mitchell Sonya, Leng Shuangying, Meng Songmei, Gallagher James W, Shelness Gregory S, Morris Gabriel S, Mahan James, Frase Sharon, Mansbach Charles M, Weinberg Richard B, Black Dennis D
Abstract excerpt
Intestinal apolipoprotein A-IV expression is highly regulated by dietary lipid in newborn swine, suggesting a role in lipid absorption. Constitutive overexpression of apoA-IV in newborn swine enterocytes enhances basolateral secretion of triacylglycerol (TG) in TG-rich lipoproteins 4.9-fold (Lu, S., Yao, Y., Meng, S., Cheng, X., and Black, D. D. (2002) J. Biol. Chem. 277, 31929-31937). To investigate the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.