Article
Expression of calcineurin and its interacting proteins in epileptic fowl.
Journal of neurochemistry - 1 Jan 2006
Lakshmikuttyamma Ashakumary, Selvakumar Ponniah, Charavaryamath Chandrashekhar, Singh Baljit, Tuchek John, Sharma Rajendra K
Abstract excerpt
Calcineurin (CaN), a Ca2+-calmodulin (CaM)-dependent protein phosphatase, is important for Ca2+-mediated signal transduction. The main objective of this study was to examine the potential role of CaN in epileptic brain and its involvement in neuronal apoptosis. We investigated CaN expression and its interaction with various signaling molecules in normal, carrier and epileptic brain tissues of chicken. Our results...
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