Article
The detection of minimal residual disease in acute lymphoblastic leukaemia.
Blood reviews - 1 Jun 1992
Potter M N
Abstract excerpt
The detection of minimal residual disease in acute lymphoblastic leukaemia (ALL) can be achieved by assessing leukaemia-specific features at a cellular, chromosomal or molecular level. The application of the polymerase chain reaction to the amplification of leukaemia-specific chromosomal translocations and clone-specific immunoglobulin and T-cell receptor gene rearrangements allows assessment of the majority of...
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