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Article

Evidence for the involvement of dominant-negative Notch molecules in the normal course of Drosophila development.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Feb 2006

LeComte Matthew, Wesley Umadevi V, Mok Lee-Peng, Shepherd Andrew, Wesley Cedric

Abstract excerpt

Notch signaling is used to specify cell types during animal development. A high level specifies one cell type, whereas a low level specifies the alternate type. The effector of Notch signaling is the Notch intracellular domain. Upon its release from the plasma membrane in response to Delta binding the Notch extracellular domain, the Notch intracellular domain combines with the transcription factor Suppressor of...

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PMID: 16331645
DOI: 10.1002/dvdy.20650

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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