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Article

Expression and localization of placenta growth factor and PlGF receptors in human meningiomas

1 Sept 1999

Abstract excerpt

It has previously been suggested that in human brain tumours, endothelial cell proliferation during angiogenesis is regulated by a paracrine mechanism involving vascular endothelial growth factor (VEGF) and its receptors (VEGF receptor 1 and VEGF receptor 2). The mechanism of growth factor up-regulation is based on hypoxic activation of mRNA expression and mRNA stabilization and genetic events, leading to an...

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Identifiers

PMID: 10451490
DOI: 10.1002/(sici)1096-9896(199909)189:1<66::aid-path390>3.0.co;2-x

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