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Article

Brg1 is required for murine neural stem cell maintenance and gliogenesis.

Developmental biology - 15 Jan 2006

Matsumoto Steven, Banine Fatima, Struve Jaime, Xing Rubing, Adams Chris, Liu Ying, Metzger Daniel, Chambon Pierre, Rao Mahendra S, Sherman Larry S

Abstract excerpt

Epigenetic alterations in cell-type-specific gene expression control the transition of neural stem cells (NSCs) from predominantly neurogenic to predominantly gliogenic phases of differentiation, but how this switch occurs is unclear. Here, we show that brahma-related gene 1 (Brg1), an ATP-dependent chromatin remodeling factor, is required for the repression of neuronal commitment and the maintenance of NSCs in a...

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Identifiers

PMID: 16330018
DOI: 10.1016/j.ydbio.2005.10.044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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