Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Potential for expanded power in linkage studies using the ALLEGRO and MERLIN software programs.

Journal of medical genetics - 1 Dec 2005

Rampersaud E, Scott W K, Hauser E R, Speer M C

Abstract excerpt

Multipoint linkage analysis in complex diseases requires the use of fast algorithms that can handle many markers and a large number of moderately sized pedigrees with unknown mode of inheritance. This need has led to the development of several competitive software programs. We recently completed a genomic screen of neural tube defects using GENEHUNTER-PLUS and the more recent ALLEGRO. The ALLEGRO software was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Algorithms
Share to Computational Biology
Share to Genetic Linkage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Linkage Disequilibrium

Share to Lod Score

Share to Neural Tube Defects

Share to Pedigree

Share to Software

Source

Open in PubMed Open full text

Identifiers

PMID: 16326825
DOI: 10.1136/jmg.2005.032029
PMCID: PMC1735966

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Potential for expanded power in linkage studies using the ALLEGRO and MERLIN software programs.PMID 16326825Read ↗

easyLINKAGE-Plus--automated linkage analyses using large-scale SNP data.Semantic proximity Read ↗

Faster linkage analysis computations for pedigrees with loops or unused alleles.Semantic proximity Read ↗

SNPLINK: multipoint linkage analysis of densely distributed SNP data incorporating automated linkage disequilibrium removal.Semantic proximity Read ↗

Whole genomewide linkage screen for neural tube defects reveals regions of interest on chromosomes 7 and 10.Semantic proximity Read ↗

A survey of current software for linkage analysis.Semantic proximity Read ↗

High-density single nucleotide polymorphism screen in a large multiplex neural tube defect family refines linkage to loci at 7p21.1-pter and 2q33.1-q35.Semantic proximity Read ↗

Efficient multipoint linkage analysis through reduction of inheritance space.Semantic proximity Read ↗

Exact genetic linkage computations for general pedigrees.Semantic proximity Read ↗

Parameter estimation and quantitative parametric linkage analysis with GENEHUNTER-QMOD.Semantic proximity Read ↗

LINKAGE-1: a PASCAL computer program for the detection and analysis of genetic linkage.Semantic proximity Read ↗

ALOHOMORA: a tool for linkage analysis using 10K SNP array data.Semantic proximity Read ↗

Performance of the nonparametric linkage analysis using GENEHUNTER for a complicated genetic disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.