Article
Weak acid and alkali stress regulate phosphatidylinositol bisphosphate synthesis in Saccharomyces cerevisiae.
The Biochemical journal - 1 Apr 2006
Mollapour Mehdi, Phelan John P, Millson Stefan H, Piper Peter W, Cooke Frank T
Abstract excerpt
Weak organic acids are used as food preservatives to inhibit the growth of spoilage yeasts, including Saccharomyces cerevisiae. Long-term adaptation to weak acids requires the increased expression of the ATP-binding cassette transporter Pdr12p, which catalyses the active efflux of the weak acids from the cytosol; however, very little is known about the signalling events immediately following application of weak...
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