Article
Visualization of alternative splicing in vivo.
Methods (San Diego, Calif.) - 1 Dec 2005
Kemp Paul R, Ellis Peter D, Smith Christopher W J
Abstract excerpt
The analysis of sequences required for alternative splicing of mRNA has predominantly been performed using cell culture systems. However, the phenotype of cultured cells is almost invariably different from that of cells in the intact animal. It is therefore possible that there are significant differences in the regulation of specific splicing reactions in vivo compared to in cell culture. Here, we describe...
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