Two proteins with 6‐cys motifs are required for malarial parasites to commit to infection of the hepatocyte

Abstract excerpt

Many intracellular pathogens have host cells suitable for their proliferation, and selectively invade them using specific host-parasite interactions. Malarial sporozoites, the liver-invasive forms, are effectively targeted to hepatocytes and proliferate in them. So far, however, sporozoite molecules that mediate the specific infection of hepatocytes remain unknown. Here we report that two proteins, Pbs36p and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Malaria Research and Control
• Share to Mosquito-borne diseases and control
• Share to Parasites and Host Interactions