Article
The variable number of tandem repeats element in DAT1 regulates in vitro dopamine transporter density.
BMC genetics - 27 Nov 2005
VanNess Sidney H, Owens Michael J, Kilts Clinton D
Abstract excerpt
BACKGROUND: A 40-bp variable number of tandem repeats (VNTR) polymorphism exists in the 15th exon of DAT1, the gene encoding the human dopamine transporter (DAT). Though the VNTR resides in a region encoding the 3' untranslated region (UTR) and does not alter the protein's amino acid sequence, the prevalent 10-repeat variant has shown both linkage and association to Attention Deficit Hyperactivity Disorder...
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