Article
ERBB2 kinase domain mutation in a gastric cancer metastasis.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Oct 2005
Lee Jong Woo, Soung Young Hwa, Kim Su Young, Park Won Sang, Nam Suk Woo, Kim Sang Ho, Lee Jung Young, Yoo Nam Jin, Lee Sug Hyung
Abstract excerpt
ERBB2 is a member of the epidermal growth factor receptor (EGFR) family. Recent studies revealed that the kinase domain of the ERBB2 gene was mutated in human cancers, including gastric cancer. Despite the importance of cancer metastasis in the pathogenesis of cancers, data on the ERBB2 kinase domain mutation in cancer metastasis are lacking. In this study, to explore the possibility that ERBB2 mutation is...
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