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Article

Mechanisms of urodele limb regeneration

1 Aug 2017

Abstract excerpt

This review explores the historical and current state of our knowledge about urodele limb regeneration. Topics discussed are (1) blastema formation by the proteolytic histolysis of limb tissues to release resident stem cells and mononucleate cells that undergo dedifferentiation, cell cycle entry and accumulation under the apical epidermal cap. (2) The origin, phenotypic memory, and positional memory of blastema...

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PMID: 29299322
DOI: 10.1002/reg2.92

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