Article
Ret deficiency in mice impairs the development of A5 and A6 neurons and the functional maturation of the respiratory rhythm.
The European journal of neuroscience - 1 Nov 2005
Viemari J C, Maussion G, Bévengut M, Burnet H, Pequignot J M, Népote V, Pachnis V, Simonneau M, Hilaire G
Abstract excerpt
Although a normal respiratory rhythm is vital at birth, little is known about the genetic factors controlling the prenatal maturation of the respiratory network in mammals. In Phox2a mutant mice, which do not express A6 neurons, we previously hypothesized that the release of endogenous norepinephrine by A6 neurons is required for a normal respiratory rhythm to occur at birth. Here we investigated the role of the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.