Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Deubiquitinating Activity Is Conserved in the Large Tegument Protein of the Herpesviridae

23 Nov 2005

Abstract excerpt

The largest tegument protein of herpes simplex virus 1 (HSV-1), UL36, contains a novel deubiquitinating activity embedded in it. All members of the Herpesviridae contain a homologue of HSV-1 UL36, the N-terminal segments of which show perfect conservation of those residues implicated in catalysis. For murine cytomegalovirus and Epstein-Barr virus, chosen as representatives of the beta- and gammaherpesvirus...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16306630
DOI: 10.1128/jvi.79.24.15582-15585.2005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Deubiquitinating Activity Is Conserved in the Large Tegument Protein of the HerpesviridaePMID 16306630Read ↗

Essential role of HCMV deubiquitinase in promoting oncogenesis by targeting anti-viral innate immune signaling pathwaysSemantic proximity Read ↗

Epstein-Barr Virus Encodes Three Bona Fide Ubiquitin-Specific ProteasesSemantic proximity Read ↗

A herpesvirus ubiquitin-specific protease is critical for efficient T cell lymphoma formation.Semantic proximity Read ↗

Structure of a herpesvirus-encoded cysteine protease reveals a unique class of deubiquitinating enzymes.Semantic proximity Read ↗

Epstein-Barr Virus Large Tegument Protein BPLF1 Contributes to Innate Immune Evasion through Interference with Toll-Like Receptor SignalingSemantic proximity Read ↗

Herpes Simplex Virus Type 2 UL56 Interacts with the Ubiquitin Ligase Nedd4 and Increases Its UbiquitinationSemantic proximity Read ↗

Identification of functional domains within the essential large tegument protein pUL36 of pseudorabies virus.Semantic proximity Read ↗

Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein.Semantic proximity Read ↗

Protein kinases conserved in herpesviruses potentially share a function mimicking the cellular protein kinase cdc2Semantic proximity Read ↗

Conserved Tryptophan Motifs in the Large Tegument Protein pUL36 Are Required for Efficient Secondary Envelopment of Herpes Simplex Virus Capsids.Semantic proximity Read ↗

Human Herpesvirus 1 UL24 Gene Encodes a Potential PD-(D/E)XK EndonucleaseSemantic proximity Read ↗

Activity profiling of deubiquitinating enzymes in cervical carcinoma biopsies and cell linesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.