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Article

Nuclear translocation of the pro-apoptotic Bcl-2 family member Bok induces apoptosis.

Molecular carcinogenesis - 1 Feb 2006

Bartholomeusz Geoffrey, Wu Yadi, Ali Seyed Mohamad, Xia Weiya, Kwong Ka-Yin, Hortobagyi Gabriel, Hung Mien-Chie

Abstract excerpt

The anti-apoptotic members of the Bcl-2 family, such as Bcl-2 and Bcl-XL, play a central role in preventing the induction of apoptosis via the intrinsic apoptotic pathway. It has been previously shown that induction of apoptosis by the pro-apoptotic Bcl-2 family member Bok is not antagonized by either Bcl-2 or Bcl-xL, suggesting that Bok might have a unique role in the apoptotic cascade. We showed here that human...

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PMID: 16302269
DOI: 10.1002/mc.20156

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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