Article
Overexpression of the Del1 gene causes dendritic branching in the mouse mesentery.
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology - 1 Dec 2005
Hidai Chiaki, Kawana Masatoshi, Habu Kiyoshi, Kazama Hiromi, Kawase Yosuke, Iwata Takamitsu, Suzuki Hiroshi, Quertermous Thomas, Kokubun Shinichiro
Abstract excerpt
In the present study, we established transgenic mice overexpressing Del1, a ligand of integrins, to examine the effect of overexpression of Del1 on vascular morphogenesis. In the wild-type mouse, mesenteric vessels are shaped like rakes consisting of a long stalk and short branches at the periphery. In contrast, those in transgenic mice showed typical dendritic architecture consisting of a few large primary...
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