Plasmodium falciparum: polymorphism in the MSP-1 gene in Indian isolates and predominance of certain alleles in cerebral malaria.

doi:10.1016/j.exppara.2005.10.002

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Article

Plasmodium falciparum: polymorphism in the MSP-1 gene in Indian isolates and predominance of certain alleles in cerebral malaria.

Experimental parasitology - 1 Mar 2006

Umar Farooq, Dubey M L, Malla N, Mahajan R C

Abstract excerpt

Polymorphism in the block-2 region of merozoite surface protein-1 gene in 69 North Indian Plasmodium falciparum isolates was studied by PCR and RFLP using Dra-1 endonuclease. On the basis of molecular weight of the PCR products, considerable size polymorphism in target gene was seen and 69 isolates were classified into five allelic types. On RFLP, the isolates in three allelic types were further divided into two...

Topics

Adolescent
Adult
Alleles
Animals
Child
Deoxyribonucleases, Type II Site-Specific
Genetic Variation
Humans
India
Malaria, Cerebral
Merozoite Surface Protein 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Middle Aged

Molecular Weight

Plasmodium falciparum

Polymerase Chain Reaction

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 16300763
DOI: 10.1016/j.exppara.2005.10.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-16300763-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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