Article
Genetic structure of Plasmodium falciparum field isolates in eastern and north-eastern India.
Malaria journal - 21 May 2007
Joshi Hema, Valecha Neena, Verma Anju, Kaul Asha, Mallick Prashant K, Shalini Sneh, Prajapati Surendra K, Sharma Surya K, Dev Vas, Biswas Sukla, Nanda Nutan, Malhotra M S, Subbarao Sarala K, Dash Aditya P
Abstract excerpt
BACKGROUND: Molecular techniques have facilitated the studies on genetic diversity of Plasmodium species particularly from field isolates collected directly from patients. The msp-1 and msp-2 are highly polymorphic markers and the large allelic polymorphism has been reported in the block 2 of the msp-1 gene and the central repetitive domain (block3) of the msp-2 gene. Families differing in nucleotide sequences...
Topics
- Amino Acid Sequence
- Animals
- Antigens, Protozoan
- Genetic Variation
- Genotype
- Humans
- India
- Malaria, Falciparum
- Merozoite Surface Protein 1
- Molecular Sequence Data