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Article

Enhanced episodic-like memory and kindling epilepsy in a rat model of tuberous sclerosis.

Journal of neurochemistry - 1 Jan 2006

Waltereit Robert, Welzl Hans, Dichgans Johannes, Lipp Hans-Peter, Schmidt Werner J, Weller Michael

Abstract excerpt

Tuberous sclerosis complex (TSC) is a common neurological autosomal-dominant syndrome caused by mutations in the TSC1 or TSC2 genes. TSC starts in early childhood and is characterized by cerebral hamartomas (benign tumours), severe epilepsy and cognitive deficits such as mental retardation and autism. The hamartomas are characterized by loss of the remaining wild-type TSC allele, and clinical data implicate...

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Source

Identifiers

PMID: 16300636
DOI: 10.1111/j.1471-4159.2005.03538.x

Genes

TSC2
TSC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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