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Article

Attenuation of Salmonella enterica Serovar Typhimurium by altering biological functions of murein lipoprotein and lipopolysaccharide.

Infection and immunity - 1 Dec 2005

Fadl A A, Sha J, Klimpel G R, Olano J P, Galindo C L, Chopra A K

Abstract excerpt

We constructed Salmonella enterica serovar Typhimurium double-knockout mutants in which either the lipoprotein A (lppA) or the lipoprotein B (lppB) gene was deleted from an msbB-negative background strain by marker exchange mutagenesis. These mutants were highly attenuated when tested with in vitro and in vivo models of Salmonella pathogenesis.

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Identifiers

PMID: 16299345
DOI: 10.1128/IAI.73.12.8433-8436.2005
PMCID: PMC1307095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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