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Murein Lipoprotein Is a Critical Outer Membrane Component Involved in<i>Salmonella enterica</i>Serovar Typhimurium Systemic Infection

21 Jan 2005

Abstract excerpt

Lipopolysaccharide (LPS) and Braun (murein) lipoprotein (Lpp) are major components of the outer membrane of gram-negative enteric bacteria that function as potent stimulators of inflammatory and immune responses. In a previous paper, we provided evidence that two functional copies of the lipoprotein gene (lppA and lppB) located on the chromosome of Salmonella enterica serovar Typhimurium contributed to bacterial...

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PMID: 15664952
DOI: 10.1128/iai.73.2.1081-1096.2005

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