Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A Competitive Mechanism for Staphylococcal Toxin SSL7 Inhibiting the Leukocyte IgA Receptor, FcαRI, Is Revealed by SSL7 Binding at the Cα2/Cα3 Interface of IgA

18 Nov 2005

Abstract excerpt

Leukocyte recruitment and effector functions like phagocytosis and respiratory burst are key elements of immunity to infection. Pathogen survival is dependent upon the ability to overwhelm, evade or inhibit the immune system. Pathogenic group A and group B streptococci are well known to produce virulence factors that block the binding of IgA to the leukocyte IgA receptor, Fc alphaRI, thereby inhibiting...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antimicrobial Resistance in Staphylococcus
Share to Immune Response and Inflammation
Share to Streptococcal Infections and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 16293625
DOI: 10.1074/jbc.m509334200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A Competitive Mechanism for Staphylococcal Toxin SSL7 Inhibiting the Leukocyte IgA Receptor, FcαRI, Is Revealed by SSL7 Binding at the Cα2/Cα3 Interface of IgAPMID 16293625Read ↗

Structural basis for evasion of IgA immunity by <i>Staphylococcus aureus</i> revealed in the complex of SSL7 with Fc of human IgA1Semantic proximity Read ↗

Full functional activity of SSL7 requires binding of both complement C5 and IgA.Semantic proximity Read ↗

The Staphylococcal Superantigen-Like Protein 7 Binds IgA and Complement C5 and Inhibits IgA-FcαRI Binding and Serum Killing of BacteriaSemantic proximity Read ↗

Structural basis for inhibition of complement C5 by the SSL7 protein from Staphylococcus aureus.Semantic proximity Read ↗

Structural and Functional Properties of Staphylococcal Superantigen-Like Protein 4Semantic proximity Read ↗

Specificity of Staphylococcal Superantigen-Like Protein 10 toward the Human IgG1 Fc DomainSemantic proximity Read ↗

The immune evasion roles of Staphylococcus aureus protein A and impact on vaccine developmentSemantic proximity Read ↗

Molecular basis determining species specificity for TLR2 inhibition by staphylococcal superantigen-like protein 3 (SSL3)Semantic proximity Read ↗

How Streptococcus suis serotype 2 attempts to avoid attack by host immune defensesSemantic proximity Read ↗

Immune Evasion byStaphylococcus aureusSemantic proximity Read ↗

The function of TLR2 during staphylococcal diseasesSemantic proximity Read ↗

Staphylococcal Superantigen-Like Protein 10 (SSL10) induces necroptosis through TNFR1 activation of RIPK3-dependent signal pathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.