Article
Full functional activity of SSL7 requires binding of both complement C5 and IgA.
Immunology and cell biology - 1 Aug 2013
Lorenz Natalie, Clow Fiona, Radcliff Fiona J, Fraser John D
Abstract excerpt
Staphylococcus aureus is an opportunistic bacterial pathogen responsible for a range of diseases, from local skin infections through to life-threatening illnesses such as toxic shock syndrome. S. aureus produces an assortment of molecules designed to evade or subvert the host immune system. One example is the 23 kDa staphylococcal superantigen-like protein 7 (SSL7) that simultaneously binds immunoglobulin A (IgA)...
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