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Article

The differential effects of mutant p53 alleles on advanced murine lung cancer.

Cancer research - 15 Nov 2005

Jackson Erica L, Olive Kenneth P, Tuveson David A, Bronson Roderick, Crowley Denise, Brown Michael, Jacks Tyler

Abstract excerpt

We report a direct comparison of the differential effects of individual p53 mutations on lung tumor growth and progression, and the creation of a murine model of spontaneous advanced lung adenocarcinoma that closely recapitulates several aspects of advanced human pulmonary adenocarcinoma. We gene...

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Source

Identifiers

PMID: 16288016
DOI: 10.1158/0008-5472.CAN-05-2193

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16288016-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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