Article
ETO-2 associates with SCL in erythroid cells and megakaryocytes and provides repressor functions in erythropoiesis.
Molecular and cellular biology - 1 Dec 2005
Schuh Anna H, Tipping Alex J, Clark Allison J, Hamlett Isla, Guyot Boris, Iborra Francesco J, Rodriguez Patrick, Strouboulis John, Enver Tariq, Vyas Paresh, Porcher Catherine
Abstract excerpt
Lineage specification and cellular maturation require coordinated regulation of gene expression programs. In large part, this is dependent on the activator and repressor functions of protein complexes associated with tissue-specific transcriptional regulators. In this study, we have used a proteomic approach to characterize multiprotein complexes containing the key hematopoietic regulator SCL in erythroid and...
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