Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HIV-1 TAT represses transcription of the bone morphogenic protein receptor-2 in U937 monocytic cells.

Journal of leukocyte biology - 1 Jan 2006

Caldwell Robert L, Gadipatti Radhika, Lane Kirk B, Shepherd Virginia L

Abstract excerpt

The bone morphogenetic protein receptor-2 (BMPR2) is a member of the transforming growth factor-beta receptor family and is expressed on the surface of several cell types including endothelial cells and macrophages. Recently, a cause for familial primary pulmonary hypertension (FPPH) has been identified as mutations in the gene encoding BMPR2. Three forms of pulmonary hypertension (PH) exist, including PPH, FPPH,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Morphogenetic Protein Receptors, Type II
Share to Gene Products, tat

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hypertension, Pulmonary

Share to Lectins, C-Type

Share to Mannose-Binding Lectins

Share to Mannose Receptor

Share to tat Gene Products, Human Immunodeficiency Virus

Share to U937 Cells

Source

Identifiers

PMID: 16282533
DOI: 10.1189/jlb.0405194

Genes

BMPR2
BMP2
SMAD6
TAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HIV-1 TAT represses transcription of the bone morphogenic protein receptor-2 in U937 monocytic cells.PMID 16282533Read ↗

Regulation of cellular gene expression and function by the human immunodeficiency virus type 1 tat proteinSemantic proximity Read ↗

The HIV matrix protein p17 subverts nuclear receptors expression and induces a STAT1-dependent proinflammatory phenotype in monocytes.Semantic proximity Read ↗

HIV-1 Tat second exon limits the extent of Tat-mediated modulation of interferon-stimulated genes in antigen presenting cells.Semantic proximity Read ↗

Tits and bits of HIV Tat protein.Semantic proximity Read ↗

Transcriptional Regulation of the Human Toll-Like Receptor 2 Gene in Monocytes and MacrophagesSemantic proximity Read ↗

Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension.Semantic proximity Read ↗

Tat Protein Induces Human Immunodeficiency Virus Type 1 (HIV-1) Coreceptors and Promotes Infection with both Macrophage-Tropic and T-Lymphotropic HIV-1 StrainsSemantic proximity Read ↗

Sterol Regulatory Element-Binding Protein 2 Couples HIV-1 Transcription to Cholesterol Homeostasis and T Cell ActivationSemantic proximity Read ↗

Functions of Tat: the versatile protein of human immunodeficiency virus type 1Semantic proximity Read ↗

Multiple Actions of the Human Immunodeficiency Virus Type-1 Tat Protein on Microglial Cell FunctionsSemantic proximity Read ↗

HIV Proteins Regulate Bone Marker Secretion and Transcription Factor Activity in Cultured Human Osteoblasts with Consequent Potential Implications for Osteoblast Function and DevelopmentSemantic proximity Read ↗

Bcl-2 upregulation by HIV-1 tat during infection of primary human macrophages in cultureSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.