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Article

Methylenetetrahydrofolate reductase gene polymorphisms in essential hypertension relation: with the development of hypertensive end-stage renal disease.

American journal of hypertension - 1 Nov 2005

Tylicki Leszek, Födinger Manuela, Puttinger Heidemarie, Rutkowski Przemyslaw, Strozecki Pawel, Tyszko Sylwia, Rutkowski Boleslaw, Hörl Walter H

Abstract excerpt

BACKGROUND: The pathogenesis of hypertensive nephropathy is multifactoral and in addition to BP, other factors contribute to the development of this renal pathology and its progression to end-stage renal disease. These include genetic predisposition and increased pleasure level of homocysteine-intermediate protein catabolism product known to induce kidney injury. The 677C --> T polymorphism in the...

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Source

Identifiers

PMID: 16280279
DOI: 10.1016/j.amjhyper.2005.05.012

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Methylenetetrahydrofolate reductase gene polymorphisms in essential hypertension relation: with the development of hypertensive end-stage renal disease.PMID 16280279Read ↗

Association between methylenetetrahydrofolate reductase (MTHFR) C677T/A1298C polymorphisms and essential hypertension: a systematic review and meta-analysis.Semantic proximity Read ↗

Homocysteine levels, H-Hypertension, and the MTHFR C677T genotypes: A complex interactionSemantic proximity Read ↗

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