Article
Bifocal and PP1 interaction regulates targeting of the R-cell growth cone in Drosophila.
Developmental biology - 15 Dec 2005
Babu Kavita, Bahri Sami, Alphey Luke, Chia William
Abstract excerpt
Bifocal is a putative cytoskeletal regulator and a Protein phosphatase-1 (PP1) interacting protein that mediates normal photoreceptor morphology in Drosophila. We show here that Bif and PP1-87B as well as their ability to interact with each other are required for photoreceptor growth cone targeting in the larval visual system. Single mutants for bif or PP1-87B show defects in axonal projections in which the axons...
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