Article
Synovial fluid macrophages are capable of osteoclast formation and resorption.
The Journal of pathology - 1 Jan 2006
Adamopoulos I E, Sabokbar A, Wordsworth B P, Carr A, Ferguson D J, Athanasou N A
Abstract excerpt
To determine whether synovial fluid (SF) macrophages isolated from the SF of osteoarthritis (OA), rheumatoid arthritis (RA) and pyrophosphate arthropathy (PPA) joints are capable of osteoclast formation, and to investigate the cellular and humoral factors required for this to occur, SF macrophages (CD14+) were isolated from the knee joint SF from patients with OA, RA and PPA and cultured for up to 14 days with...
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