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Cell Fusion in Human Cancer: The Dark Matter Hypothesis

7 Feb 2019

Abstract excerpt

Current strategies to determine tumor × normal (TN)-hybrid cells among human cancer cells include the detection of hematopoietic markers and other mesodermal markers on tumor cells or the presence of donor DNA in cancer samples from patients who had previously received an allogenic bone marrow transplant. By doing so, several studies have demonstrated that TN-hybrid cells could be found in human cancers. However,...

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PMID: 30736482
DOI: 10.3390/cells8020132

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